Updates on key developments in genomics

All I want for Christmas is... a family history

At a time of year when many of us will be getting together with relatives, we explore the value of talking about your family's health

Genomics, the land, and the promise of new drugs

Despite its proven value, scientists and researchers are yet to harness the full medical potential of the soil. Is genomics the key?
Fertilisation IVF

Birth of world’s first gene-edited babies sparks outcry

Why is the procedure so controversial, what are the risks, and could it ever happen in the UK? We take a look at the key issues

Day in the life: clinical bioinformatician

In the latest article in our series, Eileen Gallagher introduces the increasingly important role that bioinformatics plays in today’s healthcare system

Do our genes govern our fate?

A ‘faulty’ gene can result in different outcomes for different people – penetrance and expressivity influence the impact of our genetic code
DNA pills

What is pharmacogenomics?

… and how can clinicians take advantage of advances in genomics to better predict how their patient will respond to medication?

Delivering results: the patient perspective

As genomic testing becomes more prevalent, the ability to deliver results sensitively is paramount; so what matters to your patients and their families?

Unlocking the secrets of the genome

It was once believed that 99% of our genome was made up of ‘junk’ DNA with no purpose. Recent discoveries suggest this is far from the truth

Polygenic risk scores: how useful are they?

Being able to predict an individual’s risk of common conditions is regarded by many as the holy grail. So, where are we now?

Tuberculosis: genome sequencing and new treatment

TB cases are falling worldwide, but with hard-to-treat strains more prevalent than ever, how can genomics help? And what’s new on the treatment horizon?

Your invaluable genome

Genomic data is the currency of a new era of medicine that promises incredible advances. Here, bioinformatician Nana Mensah explains why
microbe-bacteria

Love bugs? Here’s five key facts about the microbiome

The DNA in your body doesn’t just come from you, thanks to the many millions of bacteria, virus and other cells that reside in you and on you

Building on the legacy of the 100,000 Genomes Project

As the pioneering project recruits its last participants, we look forward to the NHS’s plans for a Genomic Medicine Service for all

First RNA-based therapy approved in US and Europe

Gene-silencing technique works without altering the person’s DNA, and prevents harmful proteins from being made in their cells  

70 years of genetics and genomics in healthcare

Our new timeline infographic illustrates how genetics, and later genomics, has evolved over the lifetime of the NHS

Day in the life: consultant in clinical genetics

In this third piece in our series looking at genomics careers, Dr Andrew Douglas describes a profession at the cutting edge of healthcare

Sequencing the enemy: the genomics of infectious diseases

It’s not just human genomes that interest us in healthcare – the genomes of infective organisms can help us identify, track and prevent infection

Day in the life: genetic diabetes nurse

As part of our #GenomicsConversation week, Anita Murphy talks about how a patient’s genetic information can transform their diabetes care

Rare disease, genomics and the future

In the run-up to Rare Disease Day, we outline what constitutes ‘rare’ and how genomics is used in diagnosis and management

Direct-to-consumer genetic tests at an all-time high…

… but how can healthcare professionals make sure they are equipped to support patients who are worried and distressed about their results?  

Day in the life: trainee genetic counsellor

In the first article from a new series, STP trainee Alice Coulson looks at the invaluable role of genetic counselling in today’s health service