Blog articles


Lists of genomic bases: A, T, G and C

Repeat after me: what are repeat expansion disorders?

We learn how repeating sequences in our DNA can impact on health and how genome sequencing can make a diagnostic difference
Red blood cells in bloodstream

NICE approves RNAi therapy for porphyria

This week, we look at the latest gene silencing treatment approved by NICE – this time for an acute form of porphyria
Artery with cholesterol build-up and stuck red blood cells

RNAi: a new approach to combat cholesterol

The new cholesterol drug inclisiran is currently making headlines after being approved for use in the NHS, but how does it work?
Red blood cells in bloodstream

Cell-free DNA: detecting disease

We look at how cfDNA could be used to diagnose LMD – a life-threatening condition that is currently difficult to detect

NHS to trial new multi-cancer blood test

More than 50 different types of cancer can be detected by the new test, but how will it work?
3D render of a DNA helix

What is genomic imprinting?

We explore one type of epigenetic modification, its function in our genome and the rare conditions that have been linked to it

The quadruple helix: a new epigenetic marker?

We all know what DNA looks like, or do we? We take a look at why the quadruple helix can occur and how it could unlock new avenues for cancer therapy

Analysing the epigenome: a new way to screen for cancer

Could the DNA in our bloodstream provide a way to detect cancer? Recent research looks at a novel approach to screening through a new type of blood test
Genomics lab

What is functional genomics?

'Functional genomics' is a phrase that crops up frequently in discussion around genomics, but what does it actually mean?

Omics: A cut-out-and-keep guide

You might already know about the genome, but what of the other 'omes’ that affect our health – from the microbiome to the epigenome?

Let’s talk about (biological) sex

Sex as a biological variable has not always been factored in to medical research and practice. Will that change in the era of precision medicine?

A shot of young blood: from the divine to epigenomics

Exploring the evolution of the blood transfusion, from 17th century experiments to cell rejuvenating potential of new treatments