Blog articles

DNA being transcribed to mRNA by the RNA polymerase, and several enzymes within the nucleus of a cell

RNA-based therapies: two types explained

What are RNA therapies and how are they used? We compare the two licensed types – antisense and RNA interference – to find out more

Breakthrough in the battle against neurodegenerative disease

New genomic research could shed light on the cause of two life-limiting neurodegenerative conditions and provide targets for potential therapies and treatments

Mitochondrial disease: the genomics challenge

Mitochondrial diseases are overwhelmingly genetic in origin, so why are gene therapies so difficult to develop? We take a deep dive to find out more.

Genome editing trial suggests cure for blood diseases

Recent tests have established a potential cure for sickle cell disease and beta thalassaemia by using genome editing on bone marrow stem cells

Gene duo hints at future cure for heart disease

A new study has identified an interaction between two genes that could cause cells in the heart to replicate, opening the door to the first possible curative treatment for heart disease

Back to the future of ophthalmology: 5 predictions

We take a look back at a bold paper published in 1999, 'Ophthalmology in the post-genomic era' to see how accurate its authors' predictions really were

First RNA-based therapy approved in US and Europe

Gene-silencing technique works without altering the person’s DNA, and prevents harmful proteins from being made in their cells  
Genomics lab

Genome editing: 5 key questions answered

News stories in biomedicine are being dominated by genome editing, Crispr and other methods. So what's it all about, and what might it mean for healthcare?

Gene therapy hope for sickle cell anaemia patients

A teenager with severe sickle cell anaemia has been successfully treated with a pioneering gene therapy approach

‘Omic’ insights into Parkinson’s disease

Recent research reveals potential dawn of personalised medicine for neurological disorders might be more than just 'gut feeling'

Looking good: genomic-based approaches in eye disease

Gene-based treatments for eye diseases advance in the battle against blindness and related life-threatening conditions

Gene editing meets gene therapy

Despite continued ethical debate, latest advances in gene editing technologies are poised to transform patient treatment