Updates on key developments in genomics


NHS to trial new multi-cancer blood test
More than 50 different types of cancer can be detected by the new test, but how will it work?

The need for diversity in genomic datasets
We look at a recent prostate cancer study that highlights the importance of inclusivity in genomic studies

What is genomic imprinting?
We explore one type of epigenetic modification, its function in our genome and the rare conditions that have been linked to it

Filling the gaps: sequencing a chromosome
A human chromosome has been sequenced in its entirety for the first time, but why is this breakthrough important for the future of our reference genome?

Prenatal genomics - an overview
What role can genomics play before a baby is born? We break down the screening and testing options available now – from traditional methods to new technologies

Richter’s syndrome study published
A new study by GEP fellow Niamh Appleby has found potential pathways and targets for the treatment of Richter’s syndrome – an aggressive form of adult leukaemia

Genomics and the new Covid-19 variant
What do we know about the new strain of coronavirus sweeping across the UK? And how did genomics help us get there?

Key genomic technologies of 2020: Treatments old and new
In the second part of our review of the year’s genomic highlights, we look at the breakthroughs that are helping patients with rare disease and cancer

Key genomic technologies of 2020: fighting Covid-19
In the first of two articles reflecting on this year, we look at how genomics became central to tackling an unprecedented global pandemic

Genetics and genomics on screen
As many people slow down for a festive break, Dr Jonathan Roberts considers presentations of genomics in five popular films

First polygenic cause found for neonatal diabetes
A new study has found the first ever polygenic cause for diabetes in children younger than six months of age

Researchers find ‘hidden’ coronavirus gene
A newly discovered gene within the genome of the SARS-CoV-2 virus could offer clues about its origins and a possible target for treatment

‘New’ de novo variants linked to developmental disorders
How do gene variants affect our health? We look at a recent study that has newly identified 28 genes associated with developmental disorders

Genomics first: identifying inflammatory disease
Scientists have discovered a new rare and deadly inflammatory disease in men, but how did genomics lead them to it?

Keeping genes in mind: genomics and mental illness
UCL Genetics Institute honorary professor and psychiatrist David Curtis explains the challenge of understanding mental illnesses like schizophrenia, and how recent advances in genomics could have a real impact on clinical practice

Covid-19: what’s in the genes?
We take a look at the latest developments in our understanding of the role of the human genome when it comes to disease severity

RNA-based therapies: two types explained
What are RNA therapies and how are they used? We compare the two licensed types – antisense and RNA interference – to find out more

GEP fellow publishes new study
The benefits of involving young people in genome sequencing decision making are explored by GEP fellow Dr Celine Lewis in her recently published study

Genomics in practice: obstetrics and gynaecology
Dr Edward Morris explains the important role played by genomics in the practice of obstetrics and gynaecology - and its impact on patient care

Genome UK: making the genomic dream a reality
The government has set out its vision for how the UK will harness the power and potential of genomics for the benefit of patients. Here are the top highlights