Updates on key developments in genomics

Three things we learnt from the discovery of DNA’s structure

It’s 70 years since Watson and Crick proposed DNA’s structure; we look at this milestone in our understanding of the building block of life
A baby in a blue sleep suit lies inside an incubator.

A ground-breaking new gene therapy has saved the life of its very first NHS patient

A baby girl is showing no further signs of the fatal genetic disorder metachromatic leukodystrophy after treatment with an exciting new gene therapy

A ‘world first’ in pre-emptive pharmacogenomic testing

Researchers show a 30% reduction in adverse reactions to common clinically prescribed drugs through pharmacogenomic testing
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Stories of rare disease: Sara and Freya

In this fourth and final instalment of our rare disease blog series, we look at what happened when Sara received an unexpected diagnosis from her daughter Freya’s whole genome sequencing
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Stories of rare disease: Zainab

This third article in our series for Rare Disease Day 2023 tells the story of Zainab, who was diagnosed with a non-genomic rare condition at the age of 15
An illustrated group of people, featureless and in multiple bright colours.

Stories of rare disease: Melanie and Saskia

In the second article in our series, we share the story of Melanie’s long journey to finding a genomic diagnosis for her daughter Saskia
An illustrated group of people, featureless and in multiple bright colours.

Stories of rare disease: Aisha

To kick off our blog series for Rare Disease Day 2023, we share Aisha’s story of living with Morquio syndrome and look at the impact that healthcare workers can have on a patient’s journey
A large illustrated group of featureless people in bright colours.

Stories of rare disease: Introducing our new blog series

In honour of Rare Disease Day 2023, this week we’ll be sharing patients’ stories of living with rare disease and the role genomics has played in their journeys

What are genome editing and gene therapy?

Gene therapy and genome editing technologies are increasingly being reported on in the news and discussed in medical literature, but what are they?
A row of test tubes full of neon pink liquid, each with a pipette dangling above it, drips of more pink liquid about to drop into them.

Cancer vaccines: Three things you need to know

We shine a spotlight on RNA-based immunotherapies, which are fast becoming a major healthcare focus in the UK

NHS patients to get 'early access' to new RNA cancer vaccines

NHS cancer patients will be able to access emerging RNA-based immunotherapies thanks to a newly announced partnership between BioNTech and the government
A pair of scissors snips a section out of a double helix

Base editing: What is it and what does it mean for healthcare?

This week, we take an in-depth look at the genome-editing technology that has been making headlines worldwide
A 3D image of a protein interacting with a DNA stand while two nucleosomes flank it.

Epigenomic studies spotlight new level of cancer evolution

While genomics sets the scene for cancer to grow, it isn’t the only actor – as shown by two studies that cast a light on the role of epigenomics
Stylised representation of uterus and ovaries with hexagonal pattern background

How epigenomic testing could improve cervical cancer detection

Introducing a new epigenomic test as part of routine cervical screening may help clinicians spot the signature of cervical cancer years before it develops
Close-up image of a leukaemia cell

Cancer therapy involving genome editing cures another child’s leukaemia

We look at a new type of CAR-T cell therapy that, in the world’s first use, has cured a child patient’s leukaemia

Genomics on the horizon: Three predictions for 2023

To kick off the new year, we look at three areas of genomics research and advancement to watch out for in 2023 and beyond
A magnifying glass placed over a double helix.

Looking back: Genomics in 2022 (part two)

In the second and final part of our round-up of 2022, we look back at some of the milestones reached this year in genomics research
A magnifying glass placed over a double helix.

Looking back: Genomics in 2022 (part one)

In the first of our two-part round-up of 2022, we look back at some of this year's most exciting clinical developments in genomics
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What can pop culture tell us about genetics?

Special guest author Dr Jonathan Roberts looks at how pop culture can help us think about genetics in different ways.
Five test tubes in a row, with a double helix inside each one. The double helix inside the fourth test tube from the left is red, the rest are grey.

How accurate are genomic tests?

We outline five key things to consider when answering the common patient question, “How accurate is this genomic test?”
Render of a human brain with representation of activity

Marvel star goes public on his APOE genetic link to Alzheimer's

Chris Hemsworth recently revealed his APOE4 status, which he discovered while filming a documentary on living better for longer