The perils of clinical interpretation of genomic variants
A recent US legal case puts genetic testing and laboratory best practice under scrutiny
Consciousness and the ‘brain-in-a-dish’
Could advances in genomics help neuroscientists reveal more about the power of the human brain?
Shooting the messenger: therapeutic targeting of RNA
As scientists learn more about the crucial role of ‘messenger’ molecules, many see effective targeting as the missing link in our treatment of disease
Epigenetics – the real key to everything?
It isn't all in the code. Gene alterations play a part in disease, but gene expression may ultimately prove equally - if not more - important
Genomic damage and repair: prize-winners and pioneers
Since Albert Kelner shone a light on the process of DNA repair in 1948, scientists have been working to harness the power of correction
Circulating cell free DNA in pregnancy and cancer
Improved understanding of plasma DNA is opening up new possibilities for non-invasive testing and diagnosis
Immortality, regenerative medicine, and the origin of death
Over the past century, huge advances have been made in bioengineering. But what can genomics bring to the table?
Clinical interpretation: when is a variant a mutation?
Genome sequencing produces volumes of valuable data, but what are the challenges of interpretation that gives practitioners the answers they need?
Genomics and the trouble with 'N of 1' trials
Randomised controlled trials are a rigorous way to identify cause and effect, but when it comes to rare genomic variants, connections can be hard to detect
Cancer immunotherapy: genomic insights, promises and challenges
One-in-two people are likely to develop cancer, according to new research. With advances in genomics, can we improve the outcomes?