The growing importance of genomics for rare disease

Genomic technologies are paving the way for new diagnoses, treatments and therapy for patients with rare and ultra-rare disease

Genomics and the trouble with 'N of 1' trials

Randomised controlled trials are a rigorous way to identify cause and effect, but when it comes to rare genomic variants, connections can be hard to detect

Destined for fitness? The genetic influences on exercise

Studies have identified genes that can influence a person's exercise performance and response, as well as their propensity for injury

Novel 'virotherapy' shows promise for skin cancer treatment

Modified virus known as T-vec mounts dual attack on cancer cells

Unexpected genomic findings: who wants to know?

A ground-breaking survey on health professionals, researchers and the public's attitudes towards genomics raises some important questions

Gene therapy moves towards the mainstream

While still in their infancy, gene therapy techniques could hold great promise for patients with rare diseases

CRISPR: From 'silly idea' to miracle cures?

Editing a person's genome is a high-stkes proposition. Dr Alain Li Wan Po looks at the science behind it and the ethical issues at play

Detecting Down syndrome with genomics

A major US study has shown that non-invasive prenatal testing performs better than invasive methods, but what about the UK?

State of the nation: decoding the Icelandic genome

Genomic studies are focusing not just on key diseases, as with the 100,000 Genomes Project, but on whole population groups

Can the genetic 'fat map' aid obesity prevention?

New research has discovered more than 90 genetic regions that influence obesity, tripling the number of previously known regions

The 100,000 Genomes Project – sorting fact from fiction

As the first patients are set to be recruited to the main study this month: what are the truths and myths about this Project?

Step closer to mainstream precision medicine

Rare disease diagnoses made for two of the families involved in the 100,000 Genomes Project