Description
The course focuses on the genomics techniques used for DNA sequencing, including targeted approaches, whole exome and whole genome sequencing, and RNA sequencing. You will learn how to use methodologies and technologies to investigate genomic variation and examine the use of array-based methodologies and RNA sequencing in estimating levels of protein expression, micro RNAs and long non-coding RNAs. You will also develop an understanding of how to justify approaches to the bioinformatics analysis and interpretation of omics data.
Learn from leading experts in genomics about:
- Metabolomics and proteomics, which are important for the functional interpretation of genomic data and discovery of disease biomarkers.
- Strategies employed for evaluating pathogenicity of variants for clinical reporting.
- The basis of genotyping and detection of genetic variation.
- Whole exome and whole genome sequencing, including library preparation methods, sequencing chemistries and platforms.
- Methodologies to assess the transcriptome, including RNA expression profiling (expression array) and RNA sequencing.
- Methodologies to assess the metabolome and proteome.
- How information from the transcriptome, metabolome and proteome can be applied to the interpretation of genomic information.
- Approaches to the evaluation of pathogenicity of variants in the context of an NHS clinical report.
Learning outcomes
By the end of this module you will be able to:
- Critically evaluate a range of up-to-date genomic techniques and platforms used to interrogate targeted parts of the genome or the whole genome.
- Critically evaluate the application of current genomic techniques and technologies in clinical and research settings, using examples from cancer, common and rare inherited disease, and infectious disease.
- Critically evaluate a range of techniques used to assess the transcriptome.
- Evaluate the role of metabolomics and proteomics in the functional interpretation of genomic data.
- Justify the approaches to the bioinformatics analysis and interpretation of ‘omics’ data.
- Evaluate the approaches required to assess the pathogenicity of variants identified in whole genome sequencing and other genomic technologies.
Funding rules
Funding covers course fees only and is limited to NHS healthcare professionals working in England on a permanent contract from the full range of professional backgrounds and groups (such as medicine, nursing, healthcare scientists and technologists). University entry requirements may include criteria around existing understanding and minimum English language requirements.
University entry requirements may include criteria around existing understanding and minimum English language requirements.
The Genomics Education Programme provides limited funding to the Universities listed below. Please check with your preferred university to obtain details of the programme modules and entry criteria. See below for the key steps in the application process:
Click here to view the application process for CPPD module(s) or postgraduate certificate
Click here to view the application process for extending a PGcert to a PGdip, or a PGdip to a Master’s degree
FAQs
Are applications for funding still open during the Covid-19 pandemic?
Yes. Many of our partner universities are running modules online and funding is available. Please contact your chosen university to discuss your options. You must meet the Health Education England Genomics Education Programme eligibility criteria to receive funding for modules.
I have previously applied and received funding for two modules, but would like to complete two more. Is it possible to transfer my studies to another university?
Yes. You will need to speak to your chosen university re your requirements. You must also meet the HEE GEP eligibility criteria for funding.
I have previously applied and received funding for two modules, but would like to complete two more. Is it possible to obtain funding?
Yes. You will need to speak to your chosen university re your requirements. You must also meet the HEE GEP eligibility criteria for funding
I have been awarded funding and started the programme, but I am unable to complete. What are my options?
Funding is awarded for the period specified in the application form and there is no automatic ability to defer completion of the programme. You should speak to your university in the first instance about your situation and also contact the Genomics Education Programme (GEP) team regarding funding.
You may choose to reduce the workload of your programme by switching from, for example, a full Master’s degree to a diploma or certificate. Again, you would need to contact your course provider and the GEP.
How much study time is required to undertake this programme?
Study time will vary across the course providers. You are advised to visit your preferred university’s website for more information or to contact the relevant course lead. Most modules involve around 5 days of face-to-face teaching, followed by 2-4 weeks of independent study and assessment preparation. However, distance learning options are available for most universities.
Can I build up my CPPD modules to a full Master’s, PGDip or PGCert qualification?
Funding is allocated on an individual module basis only. Candidates who meet the HEE Genomics Education Programme eligibility criteria for funding can apply for up to four funded modules in the first instance. If you wish to progress to a full Master’s or PGDip, you should discuss options with your chosen university.
I am eligible but have been refused a commissioned place – why?
This may be due to the following potential reasons:
- The university you have applied to has used up all its commissioned allocations.
- The total number of available national commissions have been fully allocated.
- We are now applying controls to the commissioned places based on healthcare profession roles to help ensure equitable access across professions on a national scale.
I am not eligible for a HEE-funded place – can I self-fund?
This should be discussed with your preferred university.
I work for an organisation that provides services to the NHS – am I eligible to apply?
Yes – please provide details of your organisation and its services for the NHS when you apply to your preferred university.
