Postgraduate Certificate in the Interpretation and Clinical Application of Genomic Data


The PGCert in Interpretation and Clinical Application of Genomic Data consists of four modules to equip you with the necessary skills and knowledge to advance your understanding in the interpretation and clinical application of genomic data.

From April 2019 we are introducing a new application process.

To apply for HEE funded modules please directly contact your chosen University. The application process flow chart can be found here.

HEE Commissioned places will be allocated on a modular basis only as funding is limited. Speak to your chosen University if you wish to complete more than one module leading to a PGCert, PGDip, or MSc qualification.

Course Description

The aim of the PGCert in the Interpretation and Clinical Application of Genomic Data is to develop the student as a self-reliant and autonomous learner, capable of independent and novel thinking and having developed the skills to enable them to apply their learning to clinical practice.

Teaching Strategy

The learning objectives will be achieved through a teaching scheme delivered through three key domains: knowledge, skills and attitudes. The acquisition of knowledge will be achieved through a blended learning approach of face-to-face/online teaching sessions and workshops and self-directed learning through online and library resources. A secure knowledge base will then provide a platform to develop the skills of data interpretation in the context of clinical phenotyping. This will primarily be achieved through engagement at workshop sessions, assignments and portfolio development. The third domain, attitude, emphasises the need for the clinician to develop the skills to effectively communicate complex genomic data and discuss ethical considerations such as the identification of incidental findings.

Core Modules

The PGCert in the Interpretation and Clinical Application of Genomic Data consists of four modules to equip you with the necessary skills and knowledge to advance your understanding in the interpretation and clinical application of genomic data.

Understanding genetic technologies

  • Demonstrate knowledge and applicability of the principles behind commonly used molecular techniques
  • Evaluate which laboratory investigations are most suitable for a given clinical scenario
  • Critically review the processes used in issuing a laboratory report from sample checking to issuing of a diagnostic report
  • Demonstrate an in depth understanding of the methodology of at least four molecular genetic techniques
  • Design a panel of genes for analysis using next generation sequencing technologies applicable to a specific clinical phenotype

Clinical Interpretation of genomic data

  • Analyse the key features of a genetic variant which affect the prior likelihood of pathogenicity
  • Critically examine the clinical context within which a genetic variant will be interpreted
  • Apply in silico variant analysis tools to evaluate genetic variants
  • Critically evaluate the report generated by in silico variant analysis tools
  • Demonstrate the interrogation of population level genomic databases with respect to a specific genetic variant
  • Demonstrate the interrogation of mutation databases with respect to a specific genetic variant
  • Critically evaluate the medical literature regarding a specific genetic variant

Communication of genetic information and ethics

  • Communicate complex genetic data to patients/families effectively and sensitively
  • Critically evaluate the ethical issues surrounding consent for genetic testing with an understanding and explanation of incidental findings.
  • Communicate complex information about variants of unknown significance effectively to patients/families
  • Evaluate the ethical considerations of genetic testing and be able to formulate cogent arguments for and against testing in specific clinical scenarios

Personal and professional development portfolio

  • Assemble a portfolio that demonstrates learning and progression in the application of genetic technologies, the interpretation of genomic data and the communication of complex genetic information to patients
  • Demonstrate application of the approaches undertaken in the clinical interpretation of genomic data
  • Critically appraise the medical literature relevant to the interpretation of genetic data
  • Reflect on the effect of genetic test results on the patient and other healthcare professionals
  • Reflect on their communication skills when imparting complex genetic information to patients/families and the language that should be used in the development of patient/family directed literature
  • Propose and justify approaches to continuing professional development

Additional information


Part Time

Course Options

Postgraduate Certificate (60 credits)

Mode of Study


Type of Course

Postgraduate Certificate (PGCert)

University Providers

St Georges, University of London




Please check the course providers website for more detailed information about start dates, length and mode of study.

Funding Rules

Funding is limited to NHS healthcare professionals working in England from the full range of professional backgrounds and groups (such as medicine, nursing, healthcare scientists and technologists).  To take the PGCert programme, individual professionals will be expected to meet the standard entry requirements for the university to which they are applying. Typically, this will include having a good first degree and minimum English language requirements. They will also need to have the support of their employing organisation.

Please check with your preferred university to obtain details of the entry criteria and timing before going through the funding application process.

Please download a visual flow diagram outlining the funding application and approval process.

Frequently Asked Questions

I have been awarded funding, started the programme but I am unable to complete the programme. What are my options?

Funding is awarded for CPPD modules only and there is no automatic ability to defer completion of the programme. You should speak to your preferred University provider in the first instance about your situation and also contact the Genomics Education Programme team regarding funding.

How much study time is required to undertake this programme?

Study time will vary across the delivery partners. You are advised to visit your preferred University website site for more information or to contact the relevant course lead. Most modules generally involve approximately 5 days of face to face teaching, followed by between 2-4 weeks of independent study and assessment preparation.

A distance learning option is provided at Queen Mary University of London.

Can I build up my CPPD modules to a full Master’s, PGDip or PGCert qualification?

The process and ability to do this will be dependent on your preferred University and you should contact them to discuss available options.

I am eligible but have been refused a commissioned place – why?

This may be due to the following potential reasons:

  • The University you have applied for has used up all its commissioned allocations
  • The total number of available national commissions have been fully allocated
  • We are now applying controls to the commissioned places based on healthcare profession roles to provide some equitable access across professions on a national scale
I am not eligible for a HEE funded commissioned place – can I self-fund?

This should be discussed with your preferred University

Do you have to have the university place confirmed before you submit an application for funding?

No – as long as the programme start date for your preferred University falls within the specified academic year for the funding application period.

I work for an organisation that provides services to the NHS – am I eligible to apply?

Yes – please provide details in the additional information section of the funding application form.

University Providers


The logos below indicate the university providers that are able to accept HEE funded applications for this course. Follow the links provided to begin your university application process.

St Georges, University of London