Genome-Based Therapeutics

Category:

In this module students will learn how genetic information contributes to drug development. This module covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity.

This module has been developed by the provider to be offered in addition to the National Genomics Education Programme Core and Optional modules.

From April 2019 we are introducing a new application process.

To apply for HEE funded modules please directly contact your chosen University. The application process flow chart can be found here.

HEE Commissioned places will be allocated on a modular basis only as funding is limited. Speak to your chosen University if you wish to complete more than one module leading to a PGCert, PGDip, or MSc qualification.

Course Description

In this module students will learn how genetic information contributes to drug development. This module covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity.

Outline of Syllabus

  1. The module will comprehensively cover the current know-how on gene and nucleic acid based therapies typically including a review of pertinent pre-clinical and clinical research related to cystic fibrosis, haemophilia, SCID and other diseases for which gene therapy and genome-based therapies have advanced over the last 10 year.
  2. Students will be introduced to basic tools related to gene and nucleic acid-based therapies such as commonly used viral and non-viral vectors and vector production methods.
  3. In addition the use of anti-sense technology, genome editing and applications involving small non-coding RNAs will be covered.
  4. Students will also learn how the identification and characterisation of mutations and polymorphisms has led to development of personalised medicines and mutation-specific treatments for a range diseases
  5. Students will be exposed to basic concepts related to intellectual property, commercialisation strategies and health economics

Additional information

Course Options

CPPD (15 credits)

Type of Course

CPPD Module

Delivery

Part Time

Experience

Intermediate

Mode of Study

Offline

University Providers

Imperial College London

Timetable

Start Date 1Start Date 2
University of Birmingham
Newcastle University
University of Manchester
University of Sheffield
Imperial College LondonFebruary 2019
Queen Marys University of London / University College London
St George’s, University of London / King’s College London
University of Cambridge
University of Southampton
University of Exeter

Please check the university providers websites for more detailed information about start dates, length and mode of study.

Funding Rules

Funding is limited to NHS healthcare professionals working in England from the full range of professional backgrounds and groups (such as medicine, nursing, healthcare scientists and technologists).  For those interested in CPPD modules, university entry requirements may include criteria around existing understanding and minimum English language requirements.

Not all universities offer the same CPPD modules. Please check with your preferred university to obtain details of the programme modules, entry criteria and timing before going through the funding application process.

Please download a visual flow diagram outlining the funding application and approval process.

Frequently Asked Questions

I have been awarded funding, started the programme but I am unable to complete the programme. What are my options?

Funding is awarded for CPPD modules only and there is no automatic ability to defer completion of the programme. You should speak to your preferred University provider in the first instance about your situation and also contact the Genomics Education Programme team regarding funding.

How much study time is required to undertake this programme?

Study time will vary across the delivery partners. You are advised to visit your preferred University website site for more information or to contact the relevant course lead. Most modules generally involve approximately 5 days of face to face teaching, followed by between 2-4 weeks of independent study and assessment preparation.

A distance learning option is provided at Queen Mary University of London.

Can I build up my CPPD modules to a full Master’s, PGDip or PGCert qualification?

The process and ability to do this will be dependent on your preferred University and you should contact them to discuss available options.

I am eligible but have been refused a commissioned place – why?

This may be due to the following potential reasons:

  • The University you have applied for has used up all its commissioned allocations
  • The total number of available national commissions have been fully allocated
  • We are now applying controls to the commissioned places based on healthcare profession roles to provide some equitable access across professions on a national scale
I am not eligible for a HEE funded commissioned place – can I self-fund?

This should be discussed with your preferred University

Do you have to have the university place confirmed before you submit an application for funding?

No – as long as the programme start date for your preferred University falls within the specified academic year for the funding application period.

I work for an organisation that provides services to the NHS – am I eligible to apply?

Yes – please provide details in the additional information section of the funding application form.

University Providers

Funded

The logos below indicate the university providers that are able to accept HEE funded applications for this course. Follow the links provided to begin your university application process.

Imperial College London