Genomics and the Patient


This module will focus on development of tools to assist the healthcare professional in their future roles delivering NGS/genomic results, including “looked for, additional clinically important findings”, i.e. unanticipated genomic findings of potential clinical significance.

This module has been developed by the provider to be offered in addition to the National Genomics Education Programme Core and Optional modules.

From April 2019 we are introducing a new application process.

To apply for HEE funded modules please directly contact your chosen University. The application process flow chart can be found here.

HEE Commissioned places will be allocated on a modular basis only as funding is limited. Speak to your chosen University if you wish to complete more than one module leading to a PGCert, PGDip, or MSc qualification.

Course Description

Using patient faculty with a range of expertise including scientific/professionals (offers received), and a group of experienced Imperial-based Faculty, this module will build the necessary skills stepwise.

Participants will identify and interpret key features of NGS and other genomics reports, and specifically develop interpretation skills that allow them to place results in context for the patient.

Outline of Syllabus

The planned module structure has been modified to specifically reflect the Feedback Protocols of the 100,000 Genomes Project, currently recruiting across the NHS.  In our experience at West London Genomic Medicine Centre (GMC), participants are generally consenting to receive all available information, i.e.:

  1. Pertinent Findings: “Known or pathogenic variants or driver mutations directly connected to the main disease that led the participant to engage in the Project”
  2. Secondary findings. “A limited number of looked-for known, pathogenic mutations of high clinical relevance”, confined to a very limited list:
    1. Hereditary non-polyposis colorectal cancer (HNPCC)/ Lynch syndrome (genes: MLH1, MSH2, MSH6, PMS2)
    2. Familial adenomatous polyposis (FAP) (gene: APC)
    3. MYH-associated polyposis (MAP)(gene: MutYH)
    4. Hereditary, breast and ovarian cancer (genes: BRCA1 and BRCA2)
    5. Von Hippel-Lindau syndrome (gene: VHL)
    6. Multiple endocrine neoplasia type 1 (gene: MEN1) –and type 2 (gene: RET)
    7. Familial medullary thyroid cancer (FMTC) (genes: RET and NTRK1)
    8. Retinoblastoma (gene: RB1)
    9. Familial hypercholesterolaemia gene: LDLR- child onset- and also APOB
  3. Parental carrier status to identify double parental carrier status, or X-linked maternal carriers, for:
    • Sickle cell anaemia
    • Cystic fibrosis
    • Beta thalassemia
    • Congenital adrenal hyperplasia
    • 21-hydroxylase deficiency
    • Alpha thalassemia
    • Spinal muscular atrophy type I
    • Duchenne muscular dystrophy
    • Adrenoleukodystrophy
    • Haemophillia A (inversion)

Thus a component of the module will be to present specific teaching on these diseases.

Additional information

Course Options

CPPD (15 credits)

Type of Course

CPPD Module


Part Time



Mode of Study


University Providers

Imperial College London


Start Date 1Start Date 2
University of Birmingham
Newcastle University
University of Manchester
University of Sheffield
Imperial College LondonJanuary 2019
Queen Marys University of London / University College London
St George’s, University of London / King’s College London
University of Cambridge
University of Southampton
University of Exeter

Please check the university providers websites for more detailed information about start dates, length and mode of study.

Funding Rules

Funding is limited to NHS healthcare professionals working in England from the full range of professional backgrounds and groups (such as medicine, nursing, healthcare scientists and technologists).  For those interested in CPPD modules, university entry requirements may include criteria around existing understanding and minimum English language requirements.

Not all universities offer the same CPPD modules. Please check with your preferred university to obtain details of the programme modules, entry criteria and timing before going through the funding application process.

Please download a visual flow diagram outlining the funding application and approval process.

Frequently Asked Questions

I have been awarded funding, started the programme but I am unable to complete the programme. What are my options?

Funding is awarded for CPPD modules only and there is no automatic ability to defer completion of the programme. You should speak to your preferred University provider in the first instance about your situation and also contact the Genomics Education Programme team regarding funding.

How much study time is required to undertake this programme?

Study time will vary across the delivery partners. You are advised to visit your preferred University website site for more information or to contact the relevant course lead. Most modules generally involve approximately 5 days of face to face teaching, followed by between 2-4 weeks of independent study and assessment preparation.

A distance learning option is provided at Queen Mary University of London.

Can I build up my CPPD modules to a full Master’s, PGDip or PGCert qualification?

The process and ability to do this will be dependent on your preferred University and you should contact them to discuss available options.

I am eligible but have been refused a commissioned place – why?

This may be due to the following potential reasons:

  • The University you have applied for has used up all its commissioned allocations
  • The total number of available national commissions have been fully allocated
  • We are now applying controls to the commissioned places based on healthcare profession roles to provide some equitable access across professions on a national scale
I am not eligible for a HEE funded commissioned place – can I self-fund?

This should be discussed with your preferred University

Do you have to have the university place confirmed before you submit an application for funding?

No – as long as the programme start date for your preferred University falls within the specified academic year for the funding application period.

I work for an organisation that provides services to the NHS – am I eligible to apply?

Yes – please provide details in the additional information section of the funding application form.

University Providers


The logos below indicate the university providers that are able to accept HEE funded applications for this course. Follow the links provided to begin your university application process.

Imperial College London