Blog articles
![](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2024/07/Cells-474857832_900px-450x150.jpg)
In vivo and ex vivo gene therapies explained
Gene therapies can take place either 'in vivo' or 'ex vivo'; we compare these two approaches and their importance in gene therapy
![A computer manipulated photo of a hand holding a pair of self-locking medical tweezer scissors and DNA helixes. The tweezer scissors are removing a small red section that is on one of a DNA helixes.](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2024/03/Genome-editing_691562550_900px-450x150.jpg)
Hereditary angioedema gene therapy hope
A CRISPR-based genome therapy has shown promising results for patients with a rare genetic swelling disorder
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World-first gene therapy trial for Hunter syndrome opens
We explore a new treatment that aims to cross the blood-brain barrier for the first time in Hunter syndrome
![A strand of stylised blue DNA on a plain background with a magnifying glass focusing on a section of the DNA strand](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2023/07/DNA-investigating_000017842986_900px-450x150.jpg)
Casgevy – how it works
In this week’s article, we revisit Casgevy and explore its utility and application in healthcare
![An illustration of a multicoloured DNA strand running vertically down the centre of the image with two hands on either side of it. The hands are wearing blue surgical gloves. One hand is holding tweezers that are gripping the DNA strand and the other hand is holding a scalpel which has sliced the DNA strand.](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2023/02/Genome-editing_corrected-450x150.jpg)
Casgevy – the first CRISPR therapy
The UK has approved a new type of gene therapy for the blood disorders sickle cell disease and beta-thalassaemia, a world-first using CRISPR technology
![An illustration of a multicoloured DNA strand running vertically down the centre of the image with two hands on either side of it. The hands are wearing blue surgical gloves. One hand is holding tweezers that are gripping the DNA strand and the other hand is holding a scalpel which has sliced the DNA strand.](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2023/02/Genome-editing_corrected-450x150.jpg)
What are genome editing and gene therapy?
Gene therapy and genome editing technologies are increasingly being reported on in the news and discussed in medical literature, but what are they?
![A pair of scissors snips a section out of a double helix](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2023/02/Vector_000085853231_gene-editing_900px-450x150.jpg)
Base editing: What is it and what does it mean for healthcare?
This week, we take an in-depth look at the genome-editing technology that has been making headlines worldwide
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'Transformational' cardiomyopathy treatment receives funding
We explore a recently funded heart muscle disease project that will use RNA therapy and gene editing in tandem
![](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2020/06/immunecell-1350x450-450x150.jpg)
Cancer vs the immune system
This week, we explore the ways cancer cells can evade our bodies’ defences and how we can fight back
![DNA helix with a piece separated from it in front of a light source](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/08/Gene-edit_1350-450-450x150.png)
Trial underway for hATTR therapy
The novel ‘one off’ treatment could change the lives of those living with the condition
![](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2020/02/gene-editing-450x150.jpg)
Key genomic technologies of 2020: treatments old and new
In the second part of our review of the year’s genomic highlights, we look at the breakthroughs that are helping patients with rare disease and cancer
Events
![A head and shoulders shot of James Patterson](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2022/12/James-Patterson-500x500-450x150.jpg)
LinkAGE Webinar 2: CRISPR
Welcome to the second of our new series of expert webinars. In this second webinar Dr James Patterson will discuss CRISPR.