Blog articles

In vivo and ex vivo gene therapies explained

Gene therapies can take place either 'in vivo' or 'ex vivo'; we compare these two approaches and their importance in gene therapy
A computer manipulated photo of a hand holding a pair of self-locking medical tweezer scissors and DNA helixes. The tweezer scissors are removing a small red section that is on one of a DNA helixes.

Hereditary angioedema gene therapy hope

A CRISPR-based genome therapy has shown promising results for patients with a rare genetic swelling disorder

World-first gene therapy trial for Hunter syndrome opens

We explore a new treatment that aims to cross the blood-brain barrier for the first time in Hunter syndrome
A strand of stylised blue DNA on a plain background with a magnifying glass focusing on a section of the DNA strand

Casgevy – how it works

In this week’s article, we revisit Casgevy and explore its utility and application in healthcare
An illustration of a multicoloured DNA strand running vertically down the centre of the image with two hands on either side of it. The hands are wearing blue surgical gloves. One hand is holding tweezers that are gripping the DNA strand and the other hand is holding a scalpel which has sliced the DNA strand.

Casgevy – the first CRISPR therapy

The UK has approved a new type of gene therapy for the blood disorders sickle cell disease and beta-thalassaemia, a world-first using CRISPR technology
An illustration of a multicoloured DNA strand running vertically down the centre of the image with two hands on either side of it. The hands are wearing blue surgical gloves. One hand is holding tweezers that are gripping the DNA strand and the other hand is holding a scalpel which has sliced the DNA strand.

What are genome editing and gene therapy?

Gene therapy and genome editing technologies are increasingly being reported on in the news and discussed in medical literature, but what are they?
A pair of scissors snips a section out of a double helix

Base editing: What is it and what does it mean for healthcare?

This week, we take an in-depth look at the genome-editing technology that has been making headlines worldwide

'Transformational' cardiomyopathy treatment receives funding

We explore a recently funded heart muscle disease project that will use RNA therapy and gene editing in tandem

Cancer vs the immune system

This week, we explore the ways cancer cells can evade our bodies’ defences and how we can fight back
DNA helix with a piece separated from it in front of a light source

Trial underway for hATTR therapy

The novel ‘one off’ treatment could change the lives of those living with the condition

Key genomic technologies of 2020: treatments old and new

In the second part of our review of the year’s genomic highlights, we look at the breakthroughs that are helping patients with rare disease and cancer

Events

A head and shoulders shot of James Patterson

LinkAGE Webinar 2: CRISPR

Welcome to the second of our new series of expert webinars. In this second webinar Dr James Patterson will discuss CRISPR.