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A comprehensive national database involving a single consent process that stores pseudonymised patient samples and health and genomic data for access by approved researchers.

Use in clinical context

The National Genomic Research Library (NGRL) is a comprehensive database that enables approved researchers to access de-identified genomic data, health data and samples. It is a partnership between NHS England and Genomics England. This central resource, linked to the NHS Genomic Medicine Service (GMS), aims to provide access to research opportunities to improve diagnoses and our understanding of health and disease, as well as accelerate the development of new biomarkers, diagnostics and therapeutic agents.

Whole genome sequencing in the NHS GMS involves a single ‘patient choice’ consent model within the clinical pathway, which covers the clinical implications of a test, as well as an offer to participate in the NGRL.

To learn more about the NGRL, see our in-depth summary

Last updated on 13th December, 2021