Pharmacogenomics and stratified health care ensure that healthcare professionals offer the ‘right treatment, for the right person, at the right time’ and is a fast developing area.
The aim of this module is to provide a comprehensive overview of the analytical strategies and techniques used in pharmacogenomics and explore some of the challenges and limitations in this field (e.g. availability of patient material for studies of adverse drug reactions which tend to be rare, allelic heterogeneity between different ethnic groups, patient compliance etc.). Biomarkers are the predictive tools for optimising drug response and preventing adverse drug reactions thus this module will also provide an overview of the different type of genomic biomarkers currently in use or emerging.
Outline Of Syllabus
- Genomic basis of: drug reaction, drug efficacy, ethnic differences in both these; and how these are applied in prescribing practice
- Use of genomic information, for targeted drug development
- Companion diagnostics and options for NHS service delivery models
- Different types and examples of genomic-targeted intervention (examples of genomically-targeted clinical, therapeutic or lifestyle choices)
- Genomic biomarkers: SNPs, variability of short sequence repeats, haplotypes, DNA modifications, e.g. methylation, deletions or insertions, copy number variants, RNA expression levels, RNA splicing, microRNA levels
- Use of biomarkers in treatments other than cancer
Funding is limited to NHS healthcare professionals working in England from the full range of professional backgrounds and groups (such as medicine, nursing, healthcare scientists and technologists). For those interested in CPPD modules, university entry requirements may include criteria around existing understanding and minimum English language requirements.
The Genomics Education Programme are limiting funding to a maximum of 3 stand alone modules in any one academic year. If your intention is to build up credits for a Postgraduate Certificate (PG Cert), a Postgraduate Diploma (PG Dip) or to gradually work towards a full Master’s, please apply for funding from the Masters in Genomic Medicine.
Not all universities offer the same CPPD modules. Please check with your preferred university to obtain details of the programme modules, entry criteria and timing before going through the funding application process.
The funding application process in full
To apply for HEE-funded CPPD modules in Genomic Medicine you will need to first apply to the Genomics Education Programme for funding to cover the module fees and you will also need to go through the CPPD module application process with your chosen university.
CPPD module applications will need to be made directly to the individual university concerned, according to their own criteria and processes.
The process for applying comprises 6 steps. Please complete all of steps 1 to 4 to ensure your application is dealt with as quickly as possible.
- First, check that you are eligible for HEE Master’s funding according to the funding rules outlined above.
- You should then decide which of the universities you will be applying to. A full list university providers are identified below. Click on their logos for more information.
- You should discuss your proposed application, as well as your application for HEE funding with your line manager.
- Having secured your manager’s approval to undertake the Master’s module(s), you should complete the appropriate university application process in addition to the HEE funding application.
- HEE Genomics Education Programme will assess completed funding applications within two weeks of receipt of your managers approval. Funding decisions will be made by the Genomics Education Programme team and ratified by the Senior Responsible Officer.
- If funding is approved, HEE Genomics Education Programme will inform:
- The applicant
- The employer
- The relevant training lead within the applicant’s HEE Local Education and Training Board
- The applicant’s NHS England Genomic Medicine Centre (where applicable).
Frequently Asked Questions
The NHS trust that employs me is not part of a designated Genomic Medicine Centre (GMC). Can I still apply for funding?
I have been awarded funding, started the programme but I am unable to complete the programme. What are my options?
Funding is awarded for the period specified in the application form and there is no automatic ability to defer completion of the programme. You should speak to your preferred University provider in the first instance about your situation and also contact the Genomics Education Programme team regarding funding.
You may choose to reduce the workload of your programme by switching from a full MSc to a Diploma or Certificate. See the relevant pages of this website for more information or contact your course provider.
How much study time is required to undertake this programme?
Study time will vary across the delivery partners. You are advised to visit your preferred University website site for more information or to contact the relevant course lead. Most modules generally involve approximately 5 days of face to face teaching, followed by between 2-4 weeks of independent study and assessment preparation.
A distance learning option is provided at Queen Mary University of London.
Can I build up my CPPD modules to a full Master’s, PGDip or PGCert qualification?
The process and ability to do this will be dependent on your preferred University and you should contact them to discuss available options.
I am eligible but have been refused a commissioned place – why?
This may be due to the following potential reasons:
- The University you have applied for has used up all its commissioned allocations
- The total number of available national commissions have been fully allocated
- We are now applying controls to the commissioned places based on healthcare profession roles to provide some equitable access across professions on a national scale
I am not eligible for a HEE funded commissioned place – can I self-fund?
This should be discussed with your preferred University
Do you have to have the university place confirmed before you submit an application for funding?
No – as long as the programme start date for your preferred University falls within the specified academic year for the funding application period.
I work for an organisation that provides services to the NHS – am I eligible to apply?
Yes – please provide details in the additional information section of the funding application form.