Pharmacogenomics and Stratified Healthcare

Category:

This module will provide a comprehensive overview of the analytical strategies and techniques used in pharmacogenomics and explores some of the challenges and limitations in this field. Also provides an overview of the different type of genomic biomarkers currently in use or emerging.

From April 2019 we are introducing a new application process.

To apply for HEE funded modules please directly contact your chosen University. The application process flow chart can be found here.

HEE Commissioned places will be allocated on a modular basis only as funding is limited. Speak to your chosen University if you wish to complete more than one module leading to a PGCert, PGDip, or MSc qualification.

Course Description

Pharmacogenomics and stratified health care ensure that healthcare professionals offer the ‘right treatment, for the right person, at the right time’ and is a fast developing area.

The aim of this module is to provide a comprehensive overview of the analytical strategies and techniques used in pharmacogenomics and explore some of the challenges and limitations in this field (e.g. availability of patient material for studies of adverse drug reactions which tend to be rare, allelic heterogeneity between different ethnic groups, patient compliance etc.). Biomarkers are the predictive tools for optimising drug response and preventing adverse drug reactions thus this module will also provide an overview of the different type of genomic biomarkers currently in use or emerging.

Outline Of Syllabus

  • Genomic basis of: drug reaction, drug efficacy, ethnic differences in both these; and how these are applied in prescribing practice
  • Use of genomic information, for targeted drug development
  • Companion diagnostics and options for NHS service delivery models
  • Different types and examples of genomic-targeted intervention (examples of genomically-targeted clinical, therapeutic or lifestyle choices)
  • Genomic biomarkers: SNPs, variability of short sequence repeats, haplotypes, DNA modifications, e.g. methylation, deletions or insertions, copy number variants, RNA expression levels, RNA splicing, microRNA levels
  • Use of biomarkers in treatments other than cancer

Additional information

Type of Course

CPPD Module

Course Options

CPPD (15 credits)

Mode of Study

Offline

Experience

Intermediate

Delivery

Part Time

University Providers

Imperial College London, Queen Marys University of London / University College London, St Georges, University of London, University of Birmingham, University of Cambridge, University of Manchester

Timetable

Start Date
University of BirminghamJanuary 2020
Newcastle University
University of ManchesterNovember 2018
University of Sheffield
Imperial College LondonFebruary 2019
Queen Marys University of London / University College London
St George’s, University of London / King’s College LondonWinter 2019
University of CambridgeNovember 2019
University of Southampton
University of ExeterMay 2019

Please check the university providers websites for more detailed information about start dates, length and mode of study.

Funding Rules

Funding is limited to NHS healthcare professionals working in England from the full range of professional backgrounds and groups (such as medicine, nursing, healthcare scientists and technologists).  For those interested in CPPD modules, university entry requirements may include criteria around existing understanding and minimum English language requirements.

Not all universities offer the same CPPD modules. Please check with your preferred university to obtain details of the programme modules, entry criteria and timing before going through the funding application process.

Please download a visual flow diagram outlining the funding application and approval process.

Frequently Asked Questions

I have been awarded funding, started the programme but I am unable to complete the programme. What are my options?

Funding is awarded for CPPD modules only and there is no automatic ability to defer completion of the programme. You should speak to your preferred University provider in the first instance about your situation and also contact the Genomics Education Programme team regarding funding.

How much study time is required to undertake this programme?

Study time will vary across the delivery partners. You are advised to visit your preferred University website site for more information or to contact the relevant course lead. Most modules generally involve approximately 5 days of face to face teaching, followed by between 2-4 weeks of independent study and assessment preparation.

A distance learning option is provided at Queen Mary University of London.

Can I build up my CPPD modules to a full Master’s, PGDip or PGCert qualification?

The process and ability to do this will be dependent on your preferred University and you should contact them to discuss available options.

I am eligible but have been refused a commissioned place – why?

This may be due to the following potential reasons:

  • The University you have applied for has used up all its commissioned allocations
  • The total number of available national commissions have been fully allocated
  • We are now applying controls to the commissioned places based on healthcare profession roles to provide some equitable access across professions on a national scale
I am not eligible for a HEE funded commissioned place – can I self-fund?

This should be discussed with your preferred University

Do you have to have the university place confirmed before you submit an application for funding?

No – as long as the programme start date for your preferred University falls within the specified academic year for the funding application period.

I work for an organisation that provides services to the NHS – am I eligible to apply?

Yes – please provide details in the additional information section of the funding application form.

University Providers

Funded

The logos below indicate the university providers that are able to accept HEE funded applications for this course. Follow the links provided to begin your university application process.

Imperial College LondonQueen Marys University of London / University College LondonSt Georges, University of LondonUniversity of BirminghamUniversity of CambridgeUniversity of Manchester