Sample Processing and DNA Extraction

Sample Processing & DNA Extraction

Genomics England and the NHS England Genomic Medicine Centres will, through the 100,000 Genomes Project, analyse whole genome sequences from tens of thousands of patients and their relatives. This will be the first time whole genome sequencing has been utilised at scale in the NHS.

The project requires standardisation of lab processes and adherence to a set of new protocols for both the handling and processing of blood and tumour samples – in order to ensure successful whole genome sequencing. These films demonstrate the correct procedures as set out by Genomics England.

Introduction


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Why watch these films?

All staff involved with sample preparation and DNA extraction will need to be equipped with the relevant knowledge and skills to be able to prepare the high quality samples which are integral to the outcomes of this project.

Who are these films aimed at?

These films are primarily targeted at those working in molecular genetics and histopathology laboratories. They can also be viewed by anyone wishing to learn more about genomics and whole genome sequencing.

What will I learn?

Those involved in the laboratory processes can obtain the knowledge and skills to allow them to prepare and process adequate samples for the 100,000 Genomes Project.

The films cover the following topics:

  • Receiving patient samples
  • Extracting DNA from blood
  • Processing omics samples
  • Processing solid tumour samples
  • Extracting DNA from solid tumour
  • The impact on NHS laboratory teams

How will I learn?

Through these short films, you will learn the current correct protocols from a range of experts, clinical scientists and histopathologists.

On completion of viewing, a short reflection exercise will provide an opportunity to demonstrate what you have learned. You will then be able to receive a record of your feedback and obtain a downloadable Certificate of Participation.

Further Information

Genomics England guidance covers both rare disease and cancer sample requirements including blood, tumour and biopsy guidance.